There's absolutely nothing stopping you (besides ambition and learning curve!) from combining your animations with 3D elements and/or effects. This is something I'm excited about trying myself. I have a number of 3D animation applications.
There are a number of ways to combine the 3D and 2D - not sure which is best because I haven't tried any of them yet.
1) take your rendered 2D animation from Anime Studio and use it as a "video texture" for a flat rectangle layer within a 3D animation program. What I mean by this is make a 2D plane within the 3D app that has the same aspect ratio as your 2D animation and import the 2D animation as a video texture map for that 2D plane - an effect known as rotoscoping (a movie within a movie).
2) The reverse of #1, you could create whatever 3D content you want - either background stills or full 3D animations or scenes, and import them into Anime Studio as a video. Then you could animate your 2D characters and props on top of the 3D background.
3) Render both your 2D animation and your 3D animation, using some techniques and trickery to make sure the timing for each is approximately synced. Then, using a video editing program, you can overlay the 2 layers, either 2D on top of 3D or vice versa. You may benefit from techniques such as "virtual green screens". This means that you will render your 3D animation over a green background or make the background layer of your 2D animation green. Then you could "cut out" this area in your video editing software so it shows through in either case.
Any of the three techniques above will probably work, and I'd probably use a combination of all 3. For example, I might use #2 to make sure my 2D animation is going to sync with my 3D animation. Then I might use #1 when I really want my 2D to interact with the 3D. As the final step, I'd use #3 to really composite everything together and add visual effects (some of which were rendered in the 3D app). The advantage of using #3 is that you can also add a lot of your sound in this step, as all video editors have sound track(s). It might be easier to add music and sound effects in this step. Though voice overs will probably have to be done within Anime Studio to ensure the lips move in sync.
Sounds complicated, but it's all doable.
If you don't have a 3D application or video editor, here are some suggestions. Keep in mine, they are very biased, and there are "better" options. But I generally use the best option in my price range, which is generally free or close to it:
Video Editors:
1.
Serif MoviePlus 5: This is a FANTASTIC, overlooked video editor. It offers infinite video and sound layers, a large number of effects, green screening, etc, etc, etc. It's pretty cheap and well worth the purchase price. A trick to save even more is to sign up for their mailing list, and eventually they'll send you an email offer that is ridiculously cheap (especially when they are about to release another version) - but that takes patience.
http://serif.com
2.
Windows Movie Maker: (comes free with Windows XP/Vista) - pretty limited in what it can do, but it works for some things - doesn't really offer multiple video layers, so it's almost useless for what I described above.
3. Most people will probably tell you to get Adobe Premier or something, but that's major overkill and horribly expensive. There are other options, like Pinnacle and Sony (Vegas) products. I like Serif MoviePlus the best because of the price and feature set.
3D Animation Applications:
1.
Blender 3D: Absolutely FREE, mega powerful open source 3D application. Blender actually competes in many ways with the features found in programs like Maya, 3D Studio Max, Lightwave, SoftImage, etc. It's not nearly as powerful, but it has everything you need and tons more to do Hollywood quality films. The main problem with it is the steep learning curve. It has many keyboard shortcuts and tricks that, once learned, can really speed things up.
2.
Bryce, Poser, Carrara: I'm grouping these together because they used to be made by the same company. Not anymore, but I still think of them as similar because they retain some arching principles. They are middle range in price and have a lot to offer. If you look around and are "in the know", you can get them for super cheap. For example, a while back the producer of Bryce offered version 5.5 for FREE! And I just recently got Carrara for the purchase price of a British 3D magazine - it was included on a CD as a promotion.
3. There are million other 3D apps, but I have used and like the ones mentioned - mainly because of value for price and ease of use (though Blender is hard to learn). These particular ones have the capability to be used as described in the 1, 2, 3 techniques described above.
Who knows if I'll even follow my own advice. I'm a lazy hobbyist and generally leave most of my projects incomplete. But I have been thinking of how cool it would be to spend more time with it.
Phil
esotropiart.com